After discovering that he’s been betrayed by his own siblings, Klaus (Joseph Morgan) teams up with an unlikely ally and sets off on a warpath, hell bent on revenge.
Mary (Adelaide Kane) goes to extremes to halt Francis (Toby Regbo) from his quest to catch Condé (Sean Teale) at any cost.
As Alaric (Matt Davis) and Jo (guest star Jodi Lyn O’Keefe) reluctantly participate in their bachelor and bachelorette parties, Damon (Ian Somerhalder) and Elena (Nina Dobrev) discuss the ramifications from an impulsive offer that Damon makes.
When Claire Novak (guest star Kathryn Love Newton) gets a lead on her mother, Amelia (guest star Leisha Hailey), who has been missing for years, Castiel (Misha Collins) asks Sam (Jared Padalecki) and Dean (Jensen Ackles) to help her.
Oliver (Stephen Amell) goes through a rigorous transformation.
A group of teens get a scare when a disheveled young pregnant woman approaches them muttering for help.
Barry (Grant Gustin), Caitlin (Danielle Panabaker), Cisco (Carlos Valdes) and Joe (Jesse L. Martin) set a trap for Wells (Tom Cavanagh).
Jane (Gina Rodriguez) is determined to do what’s best for the baby, especially after she and Rafael (Justin Baldoni) learn that the baby is breech.
Drawn together by destiny, Vera (Shantel VanSanten), Erin (Sofia Black D’Elia), Joshua (Jon Fletcher), Raul (JD Pardo) and Peter (Joel Courtney) convene together where they meet the mysterious Rose (Anna Diop).
Adelaide Kane appears on this episode of ‘Whose Line Is It Anyway?’